Keystone may refer to:
Business
Entertainment
Places
- United States
- The "Keystone State", nickname for the U.S. Commonwealth of Pennsylvania, in use by 1802
- Keystone, Colorado, a town
- Keystone, Florida, an unincorporated community
- Keystone, Indiana
- Keystone, Iowa
- Keystone, Montana
- Keystone, Nebraska
- Keystone, South Dakota, a town near Mount Rushmore
- Keystone at the Crossing, a business/shopping district located in Indianapolis, Indiana
- Keystone Heights, Florida, a small city
- Fictional
Railroads
Schools
Other uses
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